- 1 Summary
- 2 Top 3 Biohacks
- 3 What It Is
- 4 Important Notes
- 5 What Is It
- 6 What Causes It
- 7 Treatments / Applicable Biohacks
- 8 Resources
- 9 Anecdotes
- 10 References
Main Symptoms and underlying physiological cause
Top 3 Biohacks
- use 1
- use 2
- use 3
What It Is
- Symptom 1
- Symptom 2
- Symptom 3
Underlying physiological cause
bodily systems affected, environmental issues, gut, genetics, etc.
additional information, e.g. safety concerns
What Is It
Describe the symptoms of the condition.
What Causes It
- . DIET
## 4% of migraine sufferers have celiac disease ## Gluten sensitivity  ##Recurrent Hypoglycemia  ##Magnesium deficiency
- Present in up to half of migraine patients
- Routine blood tests are not indicative of magnesium status, as <2% is in the measurable, extracellular space, 67% is in the bone and 31% is located intracellular. Serum tests are ineffective, RBC is somewhat better 
- Migraine sufferers may develop magnesium deficiency due to genetic inability to absorb magnesium, inherited renal magnesium wasting, excretion of excessive amounts of magnesium due to stress, low nutritional intake, and several other reasons
- Start dose with 400mg daily. For cluster headaches, 1g/day was effective. 
- Up dose if other symptoms of deficiency are present, such as cold extremities, PMS, and leg/foot cramps
- VItamin B6 Deficiency 
## Food intolerance: use an elemental diet to check it  ### Live off of thisfor a week and see it anything changes. ### Also diagnosable through a Cyrex food sensitivity panel ## Avoid sugar, especially fructose - MAPK plays a significant role in the inflammatory process that releases CGRP, which is a significant cause of migraines 
- Elevated Estrogen Levels
## Can be reduced through taking lots of cruciferous vegetables
Vasodilatory vs Vasoconstrictive
Most headaches will fall under one of two categories: either the blood vessels in your head are dilating too much and the increased blood flow is causing pain, or the reverse is happening and the constriction is causing it. Depending on which is the root cause, there are often different treatment possibilities.
Treatments / Applicable Biohacks
If you went to an average western medicine doctor, what would they prescribe to treat it? Drugs, physical therapy, behaviors, etc.
External Trigeminal Nerve Stimulation device
Most headaches and migraines involve the trigeminal nerve. Its superior branch ends at the exit of the eye socket, underneath the skin of the forehead.
Neurostimulation of the trigeminal nerve with:
- Cefaly acute setting (high frequency, single long session) produces a sedative effect on the nervous system that relieves headache pain.
- Cefaly prevent setting (low frequency, daily short sessions) restores progressively a normal metabolism in the fronto-temporal cortex of migraineurs; that is to say an improvement of the migraine-triggering threshold, which consequently reduces the frequency of migraine attacks.
Blocks headache through vagus nerve stimulation.
- Butterbur - effective at doses of 150mg+ 
- Fevervew / Willowbark - effecgive, possibly due to serotonin 5-HT receptor blocking effects 
- 5-HTP - reduced intensity and duration of attacks in 75% of patients treated (600mg daily injection)
Foods to Eat
Foods to Avoid
Gut Health / Probiotics
Name - Joe Shmoe
Experience with the issue - What were your symptoms? How did you get it? How did it impact your life?
Treatment History - What did you try? What worked? What didn't?